Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia

Despite the high cure rates in childhood acute lymphoblastic leukemia (ALL), relapsed ALL remains a significant clinical problem. Genetic heterogeneity does not adequately explain variations in response to therapy. The chemoprotective tumor microenvironment may additionally contribute to disease rec...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Liu, Jizhong, Masurekar, Ashish, Johnson, Suzanne, Chakraborty, Sohini, Griffiths, John, Smith, Duncan, Alexander, Seema, Dempsey, Clare, Parker, Catriona, Harrison, Stephanie, Li, Yaoyong, Miller, Crispin, Di, Yujun, Ghosh, Zhumur, Krishnan, Shekhar, Saha, Vaskar
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767490/
https://ncbi.nlm.nih.gov/pubmed/26474278
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