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Molecular insights into the enzymatic diversity of flavin‐trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm

We recently reported a flavin‐trafficking protein (Ftp) in the syphilis spirochete Treponema pallidum (Ftp_Tp) as the first bacterial metal‐dependent FAD pyrophosphatase that hydrolyzes FAD into AMP and FMN in the periplasm. Orthologs of Ftp_Tp in other bacteria (formerly ApbE) appear to lack this h...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Deka, Ranjit K., Brautigam, Chad A., Liu, Wei Z., Tomchick, Diana R., Norgard, Michael V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767422/
https://ncbi.nlm.nih.gov/pubmed/26626129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.306
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