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Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes

BACKGROUND: The rs7903146-T allele in the transcription factor 7-like 2 (TCF7L2) gene has been associated with impaired pancreatic insulin secretion, enhanced liver glucose production, and an increased risk of type 2 diabetes. Nevertheless, the impact of rs7903146 on daily glucose trajectories remai...

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Publicat a:PLoS One
Autors principals: van der Kroef, Sabrina, Noordam, Raymond, Deelen, Joris, Akintola, Abimbola A., Jansen, Steffy W. M., Postmus, Iris, Wijsman, Carolien A., Beekman, Marian, Mooijaart, Simon P., Slagboom, P. Eline, van Heemst, Diana
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767367/
https://ncbi.nlm.nih.gov/pubmed/26914832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149992
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