Gonadal steroid–dependent effects on bone turnover and bone mineral density in men

BACKGROUND. Severe gonadal steroid deficiency induces bone loss in adult men; however, the specific roles of androgen and estrogen deficiency in hypogonadal bone loss are unclear. Additionally, the threshold levels of testosterone and estradiol that initiate bone loss are uncertain. METHODS. One hun...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Finkelstein, Joel S., Lee, Hang, Leder, Benjamin Z., Burnett-Bowie, Sherri-Ann M., Goldstein, David W., Hahn, Christopher W., Hirsch, Sarah C., Linker, Alex, Perros, Nicholas, Servais, Andrew B., Taylor, Alexander P., Webb, Matthew L., Youngner, Jonathan M., Yu, Elaine W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
Soggetti:
Clinical Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767351/
https://ncbi.nlm.nih.gov/pubmed/26901812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84137
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