Neonatal thymectomy reveals differentiation and plasticity within human naive T cells

The generation of naive T cells is dependent on thymic output, but in adults, the naive T cell pool is primarily maintained by peripheral proliferation. Naive T cells have long been regarded as relatively quiescent cells; however, it was recently shown that IL-8 production is a signatory effector fu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: van den Broek, Theo, Delemarre, Eveline M., Janssen, Willemijn J.M., Nievelstein, Rutger A.J., Broen, Jasper C., Tesselaar, Kiki, Borghans, Jose A.M., Nieuwenhuis, Edward E.S., Prakken, Berent J., Mokry, Michal, Jansen, Nicolaas J.G., van Wijk, Femke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767338/
https://ncbi.nlm.nih.gov/pubmed/26901814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84997
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