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Escaping Negative Selection: ILC You in the Gut

How commensal-specific T cells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth et al. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4 T cells in a form of extrathymic negative selection.

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Farkas, Adam M., Ivanov, Ivaylo I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767161/
https://ncbi.nlm.nih.gov/pubmed/26200009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.07.006
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