Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors

[Image: see text] Hydrogen sulfide (H(2)S) is a signaling molecule which plays regulatory roles in many physiological and/or pathological processes. Therefore, regulation of H(2)S levels could have great potential therapeutic value. In this work, we report the design, synthesis, and evaluation of a...

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Pubblicato in:J Med Chem
Autori principali: Zhao, Yu, Yang, Chuntao, Organ, Chelsea, Li, Zhen, Bhushan, Shashi, Otsuka, Hiro, Pacheco, Armando, Kang, Jianming, Aguilar, Hector C., Lefer, David J., Xian, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766970/
https://ncbi.nlm.nih.gov/pubmed/26317692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01033
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