Dendritic cells activated by interferon-γ/STAT1 express interleukin-31 receptor and release pro-inflammatory mediators upon interleukin-31 treatment

Interleukin 31 (IL-31) is a T cell-derived cytokine that signals via a hetero-dimeric receptor composed of IL-31 receptor alpha (IL-31RA) and oncostatin M receptor beta (OSMRB). Although several studies have aimed to investigate IL-31-mediated effects, the biological functions of this cytokine are c...

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Bibliographic Details
Published in:J Immunol
Main Authors: Horejs-Hoeck, Jutta, Schwarz, Harald, Lamprecht, Sebastian, Maier, Elisabeth, Hainzl, Stefan, Schmittner, Maria, Posselt, Gernot, Stoecklinger, Angelika, Hawranek, Thomas, Duschl, Albert
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766741/
https://ncbi.nlm.nih.gov/pubmed/22539792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101044
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