Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2

Autism spectrum disorders (ASD) are a group of devastating neurodevelopmental syndromes that affect up to 1 in 68 children. Despite advances in the identification of ASD risk genes, the mechanisms underlying ASD remain unknown. Homozygous loss-of-function mutations in Contactin Associated Protein-li...

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Udgivet i:Neuron
Main Authors: Hoffman, Ellen J., Turner, Katherine J., Fernandez, Joseph M., Cifuentes, Daniel, Ghosh, Marcus, Ijaz, Sundas, Jain, Roshan A., Kubo, Fumi, Bill, Brent R., Baier, Herwig, Granato, Michael, Barresi, Michael J. F., Wilson, Stephen W., Rihel, Jason, State, Matthew W., Giraldez, Antonio J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766582/
https://ncbi.nlm.nih.gov/pubmed/26833134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.12.039
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