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Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2

Autism spectrum disorders (ASD) are a group of devastating neurodevelopmental syndromes that affect up to 1 in 68 children. Despite advances in the identification of ASD risk genes, the mechanisms underlying ASD remain unknown. Homozygous loss-of-function mutations in Contactin Associated Protein-li...

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Détails bibliographiques
Publié dans:Neuron
Auteurs principaux: Hoffman, Ellen J., Turner, Katherine J., Fernandez, Joseph M., Cifuentes, Daniel, Ghosh, Marcus, Ijaz, Sundas, Jain, Roshan A., Kubo, Fumi, Bill, Brent R., Baier, Herwig, Granato, Michael, Barresi, Michael J. F., Wilson, Stephen W., Rihel, Jason, State, Matthew W., Giraldez, Antonio J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766582/
https://ncbi.nlm.nih.gov/pubmed/26833134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.12.039
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