Near Infrared Fluorescence (NIRF) Molecular Imaging of Oxidized LDL with an Autoantibody in Experimental Atherosclerosis

We aimed to develop a quantitative antibody-based near infrared fluorescence (NIRF) approach for the imaging of oxidized LDL in atherosclerosis. LO1, a well- characterized monoclonal autoantibody that reacts with malondialdehyde-conjugated LDL, was labeled with a NIRF dye to yield LO1-750. LO1-750 s...

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Pubblicato in:Sci Rep
Autori principali: Khamis, Ramzi Y, Woollard, Kevin J., Hyde, Gareth D., Boyle, Joseph J, Bicknell, Colin, Chang, Shang-Hung, Malik, Talat H, Hara, Tetsuya, Mauskapf, Adam, Granger, David W, Johnson, Jason L., Ntziachristos, Vasilis, Matthews, Paul M, Jaffer, Farouc A, Haskard, Dorian O
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766560/
https://ncbi.nlm.nih.gov/pubmed/26911995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21785
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