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Single-Cell Quantification of Cytosine Modifications by Hyperspectral Dark-Field Imaging

Epigenetic modifications on DNA, especially on cytosine, play a critical role in regulating gene expression and genome stability. It is known that the levels of different cytosine derivatives are highly dynamic and are regulated by a variety of factors that act on the chromatin. Here we report an op...

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Vydáno v:ACS Nano
Hlavní autoři: Wang, Xiaolei, Cui, Yi, Irudayaraj, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766098/
https://ncbi.nlm.nih.gov/pubmed/26505210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b04451
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