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Amino acids rather than glucose account for the majority of cell mass in proliferating mammalian cells

Cells must duplicate their mass in order to proliferate. Glucose and glutamine are the major nutrients consumed by proliferating mammalian cells, but the extent to which these and other nutrients contribute to cell mass is unknown. We quantified the fraction of cell mass derived from different nutri...

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Dettagli Bibliografici
Pubblicato in:Dev Cell
Autori principali: Hosios, Aaron M., Hecht, Vivian C., Danai, Laura V., Johnson, Marc O., Rathmell, Jeffrey C., Steinhauser, Matthew L., Manalis, Scott R., Vander Heiden, Matthew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766004/
https://ncbi.nlm.nih.gov/pubmed/26954548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.02.012
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