Inhaled ozone (O(3))-induces changes in serum metabolomic and liver transcriptomic profiles in rats

Air pollution has been linked to increased incidence of diabetes. Recently, we showed that ozone (O(3)) induces glucose intolerance, and increases serum leptin and epinephrine in Brown Norway rats. In this study, we hypothesized that O(3) exposure will cause systemic changes in metabolic homeostasis...

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Pubblicato in:Toxicol Appl Pharmacol
Autori principali: Miller, Desinia B., Karoly, Edward D., Jones, Jan C., Ward, William O., Vallanat, Beena D., Andrews, Debora L., Schladweiler, Mette C., Snow, Samantha J., Bass, Virginia L., Richards, Judy E., Ghio, Andrew J., Cascio, Wayne E., Ledbetter, Allen D., Kodavanti, Urmila P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765366/
https://ncbi.nlm.nih.gov/pubmed/25838073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.03.025
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