The broad-spectrum chemokine inhibitor NR58-3.14.3 modulates macrophage-mediated inflammation in the diseased retina

BACKGROUND: The activity of macrophages is implicated in the progression of retinal pathologies such as atrophic age-related macular degeneration (AMD), where they accumulate among the photoreceptor layer and subretinal space. This process is aided by the local expression of chemokines, which furnis...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Fernando, Nilisha, Natoli, Riccardo, Valter, Krisztina, Provis, Jan, Rutar, Matt
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765229/
https://ncbi.nlm.nih.gov/pubmed/26911327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0514-x
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