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Structure-based Markov random field model for representing evolutionary constraints on functional sites
BACKGROUND: Elucidating the cooperative mechanism of interconnected residues is an important component toward understanding the biological function of a protein. Coevolution analysis has been developed to model the coevolutionary information reflecting structural and functional constraints. Recently...
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Publicado no: | BMC Bioinformatics |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4765150/ https://ncbi.nlm.nih.gov/pubmed/26911566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0948-2 |
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