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A Novel Method to Simulate the Progression of Collagen Degeneration of Cartilage in the Knee: Data from the Osteoarthritis Initiative

We present a novel algorithm combined with computational modeling to simulate the development of knee osteoarthritis. The degeneration algorithm was based on excessive and cumulatively accumulated stresses within knee joint cartilage during physiological gait loading. In the algorithm, the collagen...

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Pubblicato in:Sci Rep
Autori principali: Mononen, Mika E., Tanska, Petri, Isaksson, Hanna, Korhonen, Rami K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764929/
https://ncbi.nlm.nih.gov/pubmed/26906749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21415
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