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Impaired sodium‐evoked paraventricular nucleus neuronal activation and blood pressure regulation in conscious Sprague–Dawley rats lacking central Gαi(2) proteins

AIM: We determined the role of brain Gαi(2) proteins in mediating the neural and humoral responses of conscious male Sprague–Dawley rats to acute peripheral sodium challenge. METHODS: Rats pre‐treated (24‐h) intracerebroventricularly with a targeted oligodeoxynucleotide (ODN) (25 μg per 5 μL) to dow...

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Detalhes bibliográficos
Publicado no:Acta Physiol (Oxf)
Main Authors: Carmichael, C. Y., Carmichael, A. C. T., Kuwabara, J. T., Cunningham, J. T., Wainford, R. D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764872/
https://ncbi.nlm.nih.gov/pubmed/26412230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12610
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