Intracellular delivery of antibodies by chimeric Sesbania mosaic virus (SeMV) virus like particles

The therapeutic potential of antibodies has not been fully exploited as they fail to cross cell membrane. In this article, we have tested the possibility of using plant virus based nanoparticles for intracellular delivery of antibodies. For this purpose, Sesbania mosaic virus coat protein (CP) was g...

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Vydáno v:Sci Rep
Hlavní autoři: Abraham, Ambily, Natraj, Usha, Karande, Anjali A., Gulati, Ashutosh, Murthy, Mathur R. N., Murugesan, Sathyabalan, Mukunda, Pavithra, Savithri, Handanahal S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764859/
https://ncbi.nlm.nih.gov/pubmed/26905902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21803
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