Intracellular delivery of antibodies by chimeric Sesbania mosaic virus (SeMV) virus like particles

The therapeutic potential of antibodies has not been fully exploited as they fail to cross cell membrane. In this article, we have tested the possibility of using plant virus based nanoparticles for intracellular delivery of antibodies. For this purpose, Sesbania mosaic virus coat protein (CP) was g...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abraham, Ambily, Natraj, Usha, Karande, Anjali A., Gulati, Ashutosh, Murthy, Mathur R. N., Murugesan, Sathyabalan, Mukunda, Pavithra, Savithri, Handanahal S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764859/
https://ncbi.nlm.nih.gov/pubmed/26905902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21803
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