Production of hepatitis E virus-like particles presenting multiple foreign epitopes by co-infection of recombinant baculoviruses

Hepatitis E virus (HEV) causes not only endemics via a fecal-oral route but also sporadic cases via zoonotic transmission or blood transfusion. HEV-like particles (HEV-LP) produced by using a baculovirus expression system are considered a candidate for mucosal vaccines for HEV infection. In this stu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shima, Ryoichi, Li, Tian Cheng, Sendai, Yutaka, Kataoka, Chikako, Mori, Yoshio, Abe, Takayuki, Takeda, Naokazu, Okamoto, Toru, Matsuura, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764844/
https://ncbi.nlm.nih.gov/pubmed/26905478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21638
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