Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice

Degenerative joint diseases such as osteoarthritis are characterised by aberrant region-specific bone formation and abnormal bone mineral content. A recent study suggested a role for the complement membrane attack complex in experimental models of osteoarthritis. Since CD59a is the principal regulat...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Bloom, Anja C., Collins, Fraser L., van't Hof, Rob J., Ryan, Elizabeth S., Jones, Emma, Hughes, Timothy R., Morgan, B. Paul, Erlandsson, Malin, Bokarewa, Maria, Aeschlimann, Daniel, Evans, Bronwen A.J., Williams, Anwen S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2016
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Original Full Length Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764651/
https://ncbi.nlm.nih.gov/pubmed/26721735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.12.014
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