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Exome sequencing identified null mutations in LOXL3 associated with early-onset high myopia

PURPOSE: To identify null mutations in novel genes associated with early-onset high myopia using whole exome sequencing. METHODS: Null mutations, including homozygous and compound heterozygous truncations, were selected from whole exome sequencing data for 298 probands with early-onset high myopia....

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Li, Jiali, Gao, Bei, Xiao, Xueshan, Li, Shiqiang, Jia, Xiaoyun, Sun, Wenmin, Guo, Xiangming, Zhang, Qingjiong
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764606/
https://ncbi.nlm.nih.gov/pubmed/26957899
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