Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function

Mouse CA1 pyramidal neurons express apamin-sensitive SK2-containing channels in the post-synaptic membrane, positioned close to NMDA-type (N-methyl-D-aspartate) glutamate receptors. Activated by synaptically evoked NMDAR-dependent Ca(2+) influx, the synaptic SK2-containing channels modulate excitato...

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Foilsithe in:eLife
Main Authors: Kim, Gukhan, Luján, Rafael, Schwenk, Jochen, Kelley, Melissa H, Aguado, Carolina, Watanabe, Masahiko, Fakler, Bernd, Maylie, James, Adelman, John P
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2016
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764564/
https://ncbi.nlm.nih.gov/pubmed/26880549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12637
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