In vivo expansion of regulatory T cells by low-dose interleukin-2 treatment increases allograft survival in corneal transplantation

BACKGROUND: Corneal allograft survival dramatically decreases in hosts with inflamed or vascularized recipient beds. We have previously shown that in rejected corneal allografts regulatory T cells (Tregs) demonstrate diminished Foxp3 expression and immunoregulatory function. Treatment with low doses...

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Publicado en:Transplantation
Autores principales: Tahvildari, Maryam, Omoto, Masahiro, Chen, Yihe, Emami-Naeini, Parisa, Inomata, Takenori, Dohlman, Thomas H., Kaye, Abigail E., Chauhan, Sunil K., Dana, Reza
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764457/
https://ncbi.nlm.nih.gov/pubmed/26881788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001044
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