Differentiation Therapy for Hepatocellular Carcinoma: multifaceted effects of miR-148a on tumor growth and phenotype and liver fibrosis

Death rate from HCC is increasing and liver cancer is the second leading cause of cancer-related mortality worldwide. Most patients with HCC have underlying liver cirrhosis and compromised liver function, limiting treatment options. Cirrhosis is associated with cell dedifferentiation and expansion o...

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Vydáno v:Hepatology
Hlavní autoři: Jung, Kwang Hwa, Zhang, Jing, Zhou, Chong, Shen, Hong, Gagea, Mihai, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K., Beretta, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764447/
https://ncbi.nlm.nih.gov/pubmed/26599259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28367
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