Cervical Cytology Specimen Stability in Surepath Preservative and Analytical Sensitivity for HPV Testing with the cobas and Hybrid Capture 2 Tests

None of the commercial HPV tests are U.S. FDA-approved for testing of cervical cytology specimens in SurePath preservative. Still, ~30% of HPV testing is performed on specimens in this formalin-containing preservative. Formalin-induced DNA fragmentation and cross-linking may interfere with HPV detec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tardif, Keith D., Pyne, Michael T., Malmberg, Elisabeth, Lunt, Tatum C., Schlaberg, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764333/
https://ncbi.nlm.nih.gov/pubmed/26905067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149611
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