Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes

Descriptions of insulitis in human islets throughout the natural history of type 1 diabetes are limited. We determined insulitis frequency (the percent of islets displaying insulitis to total islets), infiltrating leukocyte subtypes, and β-cell and α-cell mass in pancreata recovered from organ donor...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Campbell-Thompson, Martha, Fu, Ann, Kaddis, John S., Wasserfall, Clive, Schatz, Desmond A., Pugliese, Alberto, Atkinson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764143/
https://ncbi.nlm.nih.gov/pubmed/26581594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0779
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