CD34-selected hematopoietic stem cell transplants conditioned with myeloablative regimens and anti-thymocyte globulin for advanced myelodysplastic syndrome: limited graft-versus-host disease without increased relapse

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only curative therapy for patients with myelodysplastic syndrome (MDS). Donor T cells are critical for graft-versus-tumor effect (GVT) but carry the risk of graft-versus-host disease (GVHD). CD34 selection with immunomagnetic bead...

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Udgivet i:Biol Blood Marrow Transplant
Main Authors: Tamari, Roni, Chung, Steven, Papadopoulos, Esperanza B., Jakubowski, Ann A., Hilden, Patrick, Devlin, Sean M., Goldberg, Jenna D., Perales, Miguel-Angel, Ponce, Doris M., Sauter, Craig S., Maloy, Molly A., Herman, Dara Y, Klimek, Virginia, Young, James W., O'Reilly, Richard J., Giralt, Sergio A., Castro-Malaspina, Hugo
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764129/
https://ncbi.nlm.nih.gov/pubmed/26187863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.07.010
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