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Therapeutic Drug Monitoring and Genotypic Screening in the Clinical Use of Voriconazole
Voriconazole is an antifungal triazole that is the first line agent for treatment of invasive aspergillosis. It is metabolized by CYP2C19, CYP2C9, and CYP3A4 and demonstrates wide interpatient variability in serum concentrations. Polymorphisms in CYP2C19 contribute to variability in voriconazole pha...
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| Publicado en: | Curr Fungal Infect Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764088/ https://ncbi.nlm.nih.gov/pubmed/26918067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12281-015-0219-0 |
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