DNA methylation regulates neuronal glutamatergic synaptic scaling

Enhanced receptiveness at all synapses on a neuron that receive glutamatergic input is called cell-wide synaptic upscaling. We hypothesize that this type of synaptic plasticity may be critical for long-term memory storage within cortical circuits, a process that may also depend on epigenetic mechani...

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Udgivet i:Sci Signal
Main Authors: Meadows, Jarrod P., Guzman-Karlsson, Mikael C., Phillips, Scott, Holleman, Cassie, Posey, Jessica L., Day, Jeremy J., Hablitz, John J., Sweatt, J. David
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764068/
https://ncbi.nlm.nih.gov/pubmed/26106219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aab0715
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