Increased monocyte turnover is associated with interstitial macrophage accumulation and pulmonary tissue damage in SIV-infected rhesus macaques

We recently reported that increasing blood monocyte turnover that was associated with tissue macrophage death better predicts terminal disease progression in adult SIV-infected macaques than does declining CD4(+) T cell levels. To understand better mechanisms of pathogenesis, this study relates seve...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Cai, Yanhui, Sugimoto, Chie, Liu, David Xianhong, Midkiff, Cecily C., Alvarez, Xavier, Lackner, Andrew A., Kim, Woong-Ki, Didier, Elizabeth S., Kuroda, Marcelo J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2015
Schlagworte:
Host Defense & Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763878/
https://ncbi.nlm.nih.gov/pubmed/25780057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0914-441R
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