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A novel “humanized mouse” model for autoimmune hepatitis and the association of gut microbiota with liver inflammation

BACKGROUND: Autoimmune hepatitis (AIH) in humans is a severe inflammatory liver disease, characterized by interface hepatitis, the presence of circulating autoantibodies and hyper-gammaglobulinemia. There are two types of AIH, type-1 (AIH-1) and type-2 (AIH-2) characterized by distinct autoimmune se...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Yuksel, Muhammed, Wang, Yipeng, Tai, Ningwen, Peng, Jian, Guo, Junhua, Beland, Kathie, Lapierre, Pascal, David, Chella, Alvarez, Fernando, Colle, Isabelle, Yan, Huiping, Mieli-Vergani, Giorgina, Vergani, Diego, Ma, Yun, Wen, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763614/
https://ncbi.nlm.nih.gov/pubmed/26185095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27998
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