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The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures

Obesity-induced inflammation caused by adipocyte-macrophage interactions plays a critical role in developing insulin resistance, and peroxisome proliferator-activated receptors (PPARs) regulate inflammatory gene expression in these cells. Recently, the soy isoflavone daidzein was reported to act as...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sakamoto, Yuri, Kanatsu, Junko, Toh, Mariko, Naka, Ayano, Kondo, Kazuo, Iida, Kaoruko
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763373/
https://ncbi.nlm.nih.gov/pubmed/26901838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149676
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