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Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a

Recent studies demonstrate the functions of long non-coding RNAs (lncRNAs) in mediating gene expression at the transcriptional or translational level. Our previous study identified a Sirt1 antisense (AS) lncRNA transcribed from the Sirt1 AS strand. However, its role and regulatory mechanism is still...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Guo-qiang, Wang, Yu, Xiong, Yan, Chen, Xiao-Chang, Ma, Mei-ling, Cai, Rui, Gao, Yun, Sun, Yun-mei, Yang, Gong-She, Pang, Wei-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763196/
https://ncbi.nlm.nih.gov/pubmed/26902620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21865
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