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IGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the Brain

The generation of neurons in the adult mammalian brain requires the activation of quiescent neural stem cells (NSCs). This activation and the sequential steps of neuron formation from NSCs are regulated by a number of stimuli, which include growth factors. Insulin-like growth factor-I (IGF-I) exert...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Nieto-Estévez, Vanesa, Defterali, Çağla, Vicario-Abejón, Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763060/
https://ncbi.nlm.nih.gov/pubmed/26941597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00052
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