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In silico Analysis Revealed High-risk Single Nucleotide Polymorphisms in Human Pentraxin-3 Gene and their Impact on Innate Immune Response against Microbial Pathogens

Pentraxin-3 (PTX-3) protein is an evolutionary conserved protein that acts as a soluble pattern-recognition receptor for pathogens and plays important role in innate immune response. It recognizes various pathogens by interacting with extracellular moieties such as glactomannan of conidia (Aspergill...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Thakur, Raman, Shankar, Jata
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763014/
https://ncbi.nlm.nih.gov/pubmed/26941719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00192
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