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TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity
Myotonic dystrophy type 1 (DM1), the most common form of muscular dystrophy in adults, is caused by toxic RNAs produced from the mutant DM protein kinase (DMPK) gene. DM1 is characterized by progressive muscle wasting and weakness. Therapeutic strategies have mainly focused on targeting the toxic RN...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762946/ https://ncbi.nlm.nih.gov/pubmed/26901467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150192 |
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