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Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis
Clozapine is the only evidence-based therapy for treatment-resistant schizophrenia, but it induces agranulocytosis, a rare but potentially fatal haematological adverse reaction, in less than 1% of users. To improve safety, the drug is subject to mandatory haematological monitoring throughout the cou...
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Publicado no: | Pharmacogenomics J |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762904/ https://ncbi.nlm.nih.gov/pubmed/25732907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.5 |
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