Whole-genome mutational burden analysis of three pluripotency induction methods

There is concern that the stresses of inducing pluripotency may lead to deleterious DNA mutations in induced pluripotent stem cell (iPSC) lines, which would compromise their use for cell therapies. Here we report comparative genomic analysis of nine isogenic iPSC lines generated using three reprogra...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Bhutani, Kunal, Nazor, Kristopher L., Williams, Roy, Tran, Ha, Dai, Heng, Džakula, Željko, Cho, Edward H., Pang, Andy W. C., Rao, Mahendra, Cao, Han, Schork, Nicholas J., Loring, Jeanne F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762882/
https://ncbi.nlm.nih.gov/pubmed/26892726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10536
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky