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Characterization of Liver Monocytic Myeloid-Derived Suppressor Cells and Their Role in a Murine Model of Non-Alcoholic Fatty Liver Disease

Myeloid-derived suppressor cells (MDSCs) are potent suppressors of T cell immunity in tumors and inflammatory diseases. They are identified by surface expression of CD11b(+)Gr1(+) in mice, and CD11b(+)Gr1(+) cells accumulate in the livers of obese mice. However, many myeloid cells share these CD11b(...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yao, Liying, Abe, Masanori, Kawasaki, Keitarou, Akbar, Sheikh Mohammad Fazle, Matsuura, Bunzo, Onji, Morikazu, Hiasa, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762771/
https://ncbi.nlm.nih.gov/pubmed/26901500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149948
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