Ex Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in Melanomas

The human Matrix MetalloProtease-9 (hMMP-9) is overexpressed in tumors where it promotes the release of cancer cells thus contributing to tumor metastasis. We raised aptamers against hMMP-9, which constitutes a validated marker of malignant tumors, in order to design probes for imaging tumors in hum...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kryza, David, Debordeaux, Frédéric, Azéma, Laurent, Hassan, Aref, Paurelle, Olivier, Schulz, Jürgen, Savona-Baron, Catherine, Charignon, Elsa, Bonazza, Pauline, Taleb, Jacqueline, Fernandez, Philippe, Janier, Marc, Toulmé, Jean Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762761/
https://ncbi.nlm.nih.gov/pubmed/26901393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149387
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