Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy: The POSEIDON Randomized Trial

CONTEXT: Mesenchymal stem cells (MSCs) are under evaluation as a therapy for ischemic cardiomyopathy (ICM). Both autologous and allogeneic MSC therapies are possible; however, their safety and efficacy have not been compared. OBJECTIVE: To test whether allogeneic MSCs are as safe and effective as au...

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Udgivet i:JAMA
Main Authors: Hare, Joshua M., Fishman, Joel E., Gerstenblith, Gary, DiFede Velazquez, Darcy L., Zambrano, Juan P., Suncion, Viky Y., Tracy, Melissa, Ghersin, Eduard, Johnston, Peter V., Brinker, Jeffrey A., Breton, Elayne, Davis-Sproul, Janice, Schulman, Ivonne H., Byrnes, John, Mendizabal, Adam M., Lowery, Maureen H., Rouy, Didier, Altman, Peter, Foo, Cheryl Wong Po, Ruiz, Phillip, Amador, Alexandra, Silva, Jose Da, McNiece, Ian K., Heldman, Alan W.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762261/
https://ncbi.nlm.nih.gov/pubmed/23117550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2012.25321
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