Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion and Fibrotic Burden when Administered to Patients Undergoing Coronary Artery Bypass Grafting – The PROMETHEUS Trial

RATIONALE: While accumulating data support the efficacy of intramyocardial cell-based therapy to improve LV function in patients with chronic ischemic cardiomyopathy undergoing CABG, the underlying mechanism and impact of cell injection site remain controversial.Mesenchymal stem cells (MSCs) improve...

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Hlavní autoři: Karantalis, Vasileios, DiFede, Darcy L., Gerstenblith, Gary, Pham, Si, Symes, James, Zambrano, Juan Pablo, Fishman, Joel, Pattany, Pradip, McNiece, Ian, Conte, John, Schulman, Steven, Wu, Katherine, Shah, Ashish, Breton, Elayne, Davis-Sproul, Janice, Schwarz, Richard, Feigenbaum, Gary, Mushtaq, Muzammil, Suncion, Viky Y., Lardo, Albert C., Borrello, Ivan, Mendizabal, Adam, Karas, Tomer Z., Byrnes, John, Lowery, Maureen, Heldman, Alan W., Hare, Joshua M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104798/
https://ncbi.nlm.nih.gov/pubmed/24565698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.303180
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