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Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C.

The immunopathogenesis of autoimmune insulin-dependent diabetes in NOD mice entails defects in the development of macrophages (M phi s) from hematopoietic precursors. The present study analyzes the cellular and molecular basis underlying our previous finding that the Mø growth factor colony-stimulat...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Serreze, D V, Gaedeke, J W, Leiter, E H
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.20.9625
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