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Main path and byways: non-vesicular glutamate release by system x(c)(−) as an important modifier of glutamatergic neurotransmission
System x(c)(−) is a cystine/glutamate antiporter that exchanges extracellular cystine for intracellular glutamate. Cystine is intracellularly reduced to cysteine, a building block of GSH. As such, system x(c)(−) can regulate the antioxidant capacity of cells. Moreover, in several brain regions, syst...
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Publicado no: | J Neurochem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762049/ https://ncbi.nlm.nih.gov/pubmed/26336934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13348 |
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