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Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance

Accumulated studies demonstrate that saturated fatty acids (FAs) such as palmitic acid (PA) inhibit insulin signaling in skeletal muscle cells and monounsaturated fatty acids such as oleic acid (OA) reverse the effect of PA on insulin signaling. The detailed molecular mechanism of these opposite eff...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Chen, Xiulan, Xu, Shimeng, Wei, Shasha, Deng, Yaqin, Li, Yiran, Yang, Fuquan, Liu, Pingsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761885/
https://ncbi.nlm.nih.gov/pubmed/26899878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21454
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