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Short Communication: Preferential Killing of HIV Latently Infected CD4(+) T Cells by MALT1 Inhibitor

We report that the addition of an host paracaspase MALT1 inhibitor, MI-2, to HIV latently infected ACH-2, Jurkat E4, and J-LAT cells accelerated cell death in the presence of cell stimuli or the protein kinase C agonist, bryostatin 1. MI-2-mediated cell death correlated with the induction of the cel...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Li, Hongmei, He, Hui, Gong, Leyi, Fu, Mingui, Wang, Tony T.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761853/
https://ncbi.nlm.nih.gov/pubmed/26728103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0343
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