Modification of Platelet Proteins by 4-hydroxynonenal: Potential Mechanisms for Inhibition of Aggregation and Metabolism

Platelet aggregation is an essential response to tissue injury and is associated with activation of pro-oxidant enzymes, such as cyclooxygenase, and is also a highly energetic process. The two central energetic pathways in the cell, glycolysis and mitochondrial oxidative phosphorylation, are suscept...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Ravi, Saranya, Johnson, Michelle S., Chacko, Balu K., Kramer, Philip A., Sawada, Hirotaka, Locy, Morgan L., Wilson, Landon. S., Barnes, Stephen, Marques, Marisa B., Darley-Usmar, Victor M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761519/
https://ncbi.nlm.nih.gov/pubmed/26475426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.10.408
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