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MicroRNA regulation of F-box proteins and its role in cancer

MicroRNAs (miRNAs) are small endogenous non-coding RNAs, which play critical roles in cancer development by suppressing gene expression at the post-transcriptional level. In general, oncogenic miRNAs are upregulated in cancer, while miRNAs that act as tumor suppressors are downregulated, leading to...

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Bibliografiske detaljer
Udgivet i:Semin Cancer Biol
Main Authors: Wu, Zhao-Hui, Pfeffer, Lawrence M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761503/
https://ncbi.nlm.nih.gov/pubmed/26433073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.09.016
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